[OYC] β−Nicotinamide mononucleotide

[OYC] Product

[OYC] β−Nicotinamide mononucleotide

 

Product features in specifications:

• Molecular Formula: C11H15N2O8P
• Molecular Weight: 334.22
• Appearance: Lyophilized white powder
• Purity:  ≧95% （HPLC）
• Water contents: < 8 %
• Molecular extinction coefficient at 260 nm: 4200±200 L・mole-1・cm-1
• Recommended storage conditions: below -20℃ in dry for long-term

 

Chemical Structure:

Beta-Nicotinamide mononucleotide (NMN)는 nicotinamide에서 nicotinamide phosphoribosyltransferase (NAMPT)를 통해 생성되는 NAD+ 생합성의 중간체로, NMN 또는 nicotinamide ribotide라고도 불립니다. 최근 당뇨병, 신경 퇴행성 질환, 심장 질환 등 노화에 따른 질병의 예방 및 진단에 NMN을 적용하는 연구가 진행되면서 노화 방지를 위한 가장 뜨거운 바이오마커 중 하나로 주목받고 있습니다. OYC는 세계적인 선도 업체 중 하나로서 학계뿐만 아니라 제약업계의 기초 연구를 지원하기 위해 우수한 품질의 완전 생리활성 beta-Nicotinamide mononucleotide (NMN)를 공급하고 있습니다.

Brief summary about β-NMN:

NAD+ exists in all living organisms and is well known as a coenzyme in oxidation−reduction reaction. Recent research has drawn attention to its relation to “sirtuin” represented by NAD+−dependent protein deacetylases such as Sirt1 and Sirt3. Because Sirt1 is reported to regulate various life phenomena as aging, people is especially paying high attention to “Anti-aging effect” associated with the activated sirtuin through Sirtuin/SIRT1−activating components (STACs) as represented by resveratrol.
 

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